Treatment for BPD is complex and dependent on the individual — what works for one person may not work for another. Therapists and treatment facilities often specialize in the types of treatment offered.

No single drug has been approved by the US Food and Drug Administration to specifically treat BPD; however, certain drugs have proved to be helpful in combination with therapy. These drugs help moderate specific symptoms such as anxiety, depression, or aggression. Antidepressant drugs and mood stabilizers may be helpful for depressed and/or labile (unstable or extreme) moods. Antipsychotic drugs may be used in low doses when there are distortions in thinking or anxiety.